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Acetaminophen and caffeine and Hyoscyamine Sulfate Oral Drops

Determining the interaction of Acetaminophen and caffeine and Hyoscyamine Sulfate Oral Drops and the possibility of their joint administration.

Check result:
Acetaminophen and caffeine <> Hyoscyamine Sulfate Oral Drops
Relevance: 05.07.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Anticholinergic agents may delay and/or decrease the gastrointestinal absorption of acetaminophen by reducing gastric motility and delaying gastric emptying. However, the clinical relevance is probably minimal.

References
  • Clark JM, Seager SJ "Gastric emptying following premedication with glycopyrrolate or atropine." Br J Anaesth 55 (1983): 1195-9
  • "Product Information. Transderm Scop (scopolamine)." Ciba Self-Medication Inc, Woodbridge, NJ.
  • Nimmo J, Heading RC, Tothill P, Prescott LF "Pharmacological modification of gastric emptying: effects of propantheline and metoclopramide on paracetamol absorption." Br Med J 1 (1973): 587-9
Acetaminophen and caffeine

Generic Name: acetaminophen / caffeine

Brand name: Excedrin Mild Headache, Excedrin Quick Tab Peppermint, Excedrin Quick Tab Spearmint, Excedrin Tension Headache, Excedrin Tension Headache Caplet, Excedrin Tension Headache Express Gels, Excedrin Tension Headache Geltab, Valorin Extra, Excedrin Tension Headache Express

Synonyms: Acetaminophen and Caffeine

Hyoscyamine Sulfate Oral Drops

Generic Name: hyoscyamine

Brand name: Anaspaz, Ed Spaz, Hyosyne, Levbid, Levsin, NuLev, Symax SR, Cystospaz, Levsin SL, Cystospaz-M, Levsinex SR, Symax SL, A-Spas S/L, Donnamar, Hyosol, NuLev, Spasdel, IB-Stat, Hyospaz, Symax Duotab, Symax FasTab, HyoMax SL, HyoMax SR, HyoMax FT, HyoMax DT, HyoMax, Oscimin, A-Spaz, Levsin/SL, Colidrops, Levsinex, Symax, Symax FasTabs

Synonyms: Hyoscyamine

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.