Acetaminophen and chlorpheniramine and Rifampin Intravenous
Determining the interaction of Acetaminophen and chlorpheniramine and Rifampin Intravenous and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Rifampin may slightly decrease the therapeutic effects of acetaminophen, although at usual doses, no intervention appears to be necessary. Additionally, rifampin may increase the risk of hepatotoxicity in patients taking acetaminophen and isoniazid.
- Nolan CM, Sandblom RE, Thummel KE, Slattery JT, Nelson SD "Hepatotoxicity associated with acetaminophen usage in patients receiving multiple drug therapy for tuberculosis." Chest 105 (1994): 408-11
- Prescott LF, Critchley JA, Balali-Mood M, Pentland B "Effects of microsomal enzyme induction on paracetamol metabolism in man." Br J Clin Pharmacol 12 (1981): 149-53
- Bock KW, Wiltfang J, Blume R, Ullrich D, Bircher J "Paracetamol as a test drug to determine glucuronide formation in man: effects of inducers and of smoking." Eur J Clin Pharmacol 31 (1987): 677-83
Generic Name: acetaminophen / chlorpheniramine
Brand name: Coricidin, Coricidin HBP Cold & Flu
Synonyms: n.a.
Generic Name: rifampin
Brand name: Rifadin, Rifadin IV, Rimactane
Synonyms: Rifampin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Acetaminophen and chlorpheniramine-Rifampin Oral, Intravenous
- Acetaminophen and chlorpheniramine-Rifampin, Isoniazid, and Pyrazinamide
- Acetaminophen and chlorpheniramine-Rifamycin
- Acetaminophen and chlorpheniramine-Rifamycin Sodium
- Acetaminophen and chlorpheniramine-Rifapentine
- Acetaminophen and chlorpheniramine-Rifater
- Rifampin Intravenous-Acetaminophen and codeine
- Rifampin Intravenous-Acetaminophen and Codeine Oral Solution
- Rifampin Intravenous-Acetaminophen and Codeine Solution
- Rifampin Intravenous-Acetaminophen and Codeine Suspension
- Rifampin Intravenous-Acetaminophen and Codeine Tablets
- Rifampin Intravenous-Acetaminophen and dextromethorphan