Acetaminophen, caffeine, and magnesium salicylate and Niacin SR
Determining the interaction of Acetaminophen, caffeine, and magnesium salicylate and Niacin SR and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Salicylates may cause an elevation in serum levels of nicotinic acid. The mechanism is not completely understood. However, salicylates also significantly decrease the serum levels of nicotinuric acid--a metabolite--and some experts hypothesize that salicylic acid causes a concentration-dependent decrease in the total clearance of nicotinic acid. Such a decrease would result in the saturation of the nicotinuric acid conjugation pathway. Data are available for aspirin only. No special precautions appear to be necessary.
- Ding RW, Kolbe K, Merz B, de Vries J, Weber E, Benet LZ "Pharmacokinetics of nicotinic acid-salicylic acid interaction." Clin Pharmacol Ther 46 (1989): 642-7
Generic Name: acetaminophen / caffeine / magnesium salicylate
Brand name: KneeRelief
Synonyms: n.a.
Generic Name: niacin
Brand name: B-3-50, B3-500-Gr, Niacin SR, Niacor, Niaspan ER, Slo-Niacin
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Acetaminophen, caffeine, and magnesium salicylate-Niacin Tablets
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- Acetaminophen, caffeine, and magnesium salicylate-Niacor
- Acetaminophen, caffeine, and magnesium salicylate-Niaspan
- Acetaminophen, caffeine, and magnesium salicylate-Nic-Assist - Mint
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- Niacin SR-Acetaminophen, Chlorpheniramine, and Dextromethorphan Liquid and Syrup
- Niacin SR-Acetaminophen, Chlorpheniramine, and Dextromethorphan Suspension
- Niacin SR-Acetaminophen, chlorpheniramine, and phenylephrine
- Niacin SR-Acetaminophen, Chlorpheniramine, and Phenylephrine Effervescent Tablets