Acetaminophen, Chlorpheniramine, and Pseudoephedrine Capsules and Tablets and Ranitidine Injection
Determining the interaction of Acetaminophen, Chlorpheniramine, and Pseudoephedrine Capsules and Tablets and Ranitidine Injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Animal studies have suggested that ranitidine may potentiate the hepatotoxicity of acetaminophen, however, a double-blind placebo-controlled crossover study has failed to confirm this finding in humans. Acetaminophen dosage adjustments are not indicated.
- Rogers SA, Gale KC, Newton JF, et al "Inhibition by ranitidine of acetaminophen conjugation and its possible role in ranitidine potentiation of acetaminophen-induced hepatotoxicity." J Pharmacol Exp Ther 245 (1988): 887-94
- Jack D, Thomas M, Skidmore IF "Ranitidine and paracetamol metabolism." Lancet 2 (1985): 1067
Generic Name: acetaminophen / chlorpheniramine / pseudoephedrine
Brand name: Alka-Seltzer Plus Cold Liquigel, Comtrex Allergy Sinus, Comtrex Allergy Sinus Maximum Strength, Kolephrin, Sinutab Ex-Strength, Theraflu Maximum Strength, Singlet, Simplet, Tricom, Theraflu Flu and Cold Medicine Powder, Codimal, Tylenol Gelcap Allergy Sinus, Theraflu Sore Throat Maximum Strength, Allerest Sinus, Tylenol Cold-Child, Tylenol Allergy Sinus Caplet, Tylenol Allergy Sinus Geltab, Comtrex Allergy Sinus Night and Day, Allerest Headache Strength, Sinarest Extra Strength, Sinarest, Children's Tylenol Cold Multi-Symptom, Tylenol Allergy Sinus Gelcap, Children's Tylenol Cold, Triaminicin, Sinutab Maximum Strength Caplets, Sinutab Maximum Strength Non-Drowsy, Actifed Cold & Sinus, Theraflu Cold & Sore Throat, Theraflu Flu & Sore Throat, Allergy Sinus Maximum Strength, Cold Medicine Plus, EQ Cold Plus, Complete Sinus Relief, Sinadrin PE Complete Sinus Relief
Synonyms: Acetaminophen, chlorpheniramine, and pseudoephedrine
Generic Name: ranitidine
Brand name: Zantac
Synonyms: Ranitidine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Acetaminophen, Chlorpheniramine, and Pseudoephedrine Capsules and Tablets-Ranitidine Suspension
- Acetaminophen, Chlorpheniramine, and Pseudoephedrine Capsules and Tablets-Ranitidine Syrup
- Acetaminophen, Chlorpheniramine, and Pseudoephedrine Capsules and Tablets-Ranitidine Tablets
- Acetaminophen, Chlorpheniramine, and Pseudoephedrine Capsules and Tablets-Ranitidine Tablets and Capsules
- Acetaminophen, Chlorpheniramine, and Pseudoephedrine Capsules and Tablets-Ranolazine
- Acetaminophen, Chlorpheniramine, and Pseudoephedrine Capsules and Tablets-Ranolazine ER Tablets
- Ranitidine Injection-Acetaminophen, Chlorpheniramine, and Pseudoephedrine Liquid
- Ranitidine Injection-Acetaminophen, Chlorpheniramine, Dextromethorphan, and Guaifenesin
- Ranitidine Injection-Acetaminophen, chlorpheniramine, dextromethorphan, and pseudoephedrine
- Ranitidine Injection-Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine Liquid
- Ranitidine Injection-Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine Suspension
- Ranitidine Injection-Acetaminophen, dextromethorphan, and diphenhydramine