Drug search by name

Acetaminophen, Dextromethorphan, and Phenylephrine Capsules and Tablets and Rifampin Injection

Determining the interaction of Acetaminophen, Dextromethorphan, and Phenylephrine Capsules and Tablets and Rifampin Injection and the possibility of their joint administration.

Check result:

Acetaminophen, Dextromethorphan, and Phenylephrine Capsules and Tablets <> Rifampin Injection

Relevance: 23.07.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Rifampin may slightly decrease the therapeutic effects of acetaminophen, although at usual doses, no intervention appears to be necessary. Additionally, rifampin may increase the risk of hepatotoxicity in patients taking acetaminophen and isoniazid.

References

Nolan CM, Sandblom RE, Thummel KE, Slattery JT, Nelson SD "Hepatotoxicity associated with acetaminophen usage in patients receiving multiple drug therapy for tuberculosis." Chest 105 (1994): 408-11
Prescott LF, Critchley JA, Balali-Mood M, Pentland B "Effects of microsomal enzyme induction on paracetamol metabolism in man." Br J Clin Pharmacol 12 (1981): 149-53
Bock KW, Wiltfang J, Blume R, Ullrich D, Bircher J "Paracetamol as a test drug to determine glucuronide formation in man: effects of inducers and of smoking." Eur J Clin Pharmacol 31 (1987): 677-83

Acetaminophen, Dextromethorphan, and Phenylephrine Capsules and Tablets

Generic Name: acetaminophen / dextromethorphan / phenylephrine

Brand name: Comtrex Cold & Cough, DayQuil Cold & Flu, Daytime, Flu & Severe Cold & Cough Daytime Powder, Mapap Cold Formula, Robitussin Peak Cold Daytime Cold + Flu, Sudafed PE Pressure+Pain+Cough, Theraflu Daytime Severe Cold & Cough, Theraflu Warming Severe Cold Daytime, Tylenol Cold Multi-Symptom Daytime, Vicks Dayquil Liquicaps Cold/Flu, Contac Complete Cough, Cold & Flu Extra Strength, Tylenol Cold Daytime, Neocitran Non Drowsy Extra Strength Cold and Flu, Tylenol Cold Daytime Extra Strength, Tylenol Flu Daytime Extra Strength, Theraflu Nighttime Severe Cold & Cough, Theraflu Warming Relief Daytime Multi-Symptom Cold, Tylenol Children's Plus Cold & Cough, Theraflu Multi-Symptom Severe Cold, Day Time Cold & Flu, DayQuil Nature Fusion Cold & Flu, Theraflu ExpressMax Day Cold & Cough, Tylenol Cold Max Day, Mucinex Fast-Max Severe Cold and Sinus, Mucinex Fast-Max Congestion and Headache, Theraflu PowerPods Daytime Severe Cold, Comtrex Cold and Cough Maximum Strength, Vicks DayQuil Multi-Symptom Cold/Flu Relief

Synonyms: Acetaminophen, dextromethorphan, and phenylephrine

What is Acetaminophen, Dextromethorphan, and Phenylephrine Capsules and Tablets?

Rifampin Injection

Generic Name: rifampin

Brand name: Rifadin, Rifadin IV, Rimactane

Synonyms: Rifampin

What is Rifampin Injection?

+ Add a drug Remove all

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

The list of popular interactions