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Acetaminophen, dextromethorphan, and pseudoephedrine and Iloprost inhalation

Determining the interaction of Acetaminophen, dextromethorphan, and pseudoephedrine and Iloprost inhalation and the possibility of their joint administration.

Check result:
Acetaminophen, dextromethorphan, and pseudoephedrine <> Iloprost inhalation
Relevance: 02.07.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using pseudoephedrine together with iloprost. Using these medications together can make iloprost less effective. You should be counseled to consult with your doctor before taking over-the-counter decongestants. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Concurrent administration of decongestants or vasoconstrictors may negate the vasodilatory effects of prostacyclin analogs in patients with pulmonary hypertension.

MANAGEMENT: The use of decongestants and vasoconstrictors should probably be avoided in patients with pulmonary hypertension. Patients should be counseled to consult with their physician before taking over-the-counter decongestants such as phenylephrine and pseudoephedrine.

References
  • Hardman JG, Gilman AG, Limbird LE eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 9th ed." New York, NY: McGraw-Hill (1995):
  • "Product Information. Remodulin (treprostinil)." United Therapeutics Corp, Silver Spring, MD.
  • "Product Information. Flolan (epoprostenol)." Glaxo Wellcome, Research Triangle Park, NC.
Acetaminophen, dextromethorphan, and pseudoephedrine

Generic Name: acetaminophen / dextromethorphan / pseudoephedrine

Brand name: Alka-Seltzer Plus Flu Liquigels, Comtrex Non-Drowsy, Dayquil Liquicaps, Daytime Cold, Non-Drowsy Daytime, Robitussin Honey Flu Non-Drowsy, Theraflu Daytime Severe Cold, Theraflu Severe Cold & Congestion Non-Drowsy, Triaminic Cough & Sore Throat, Triaminic Softchew Throat Pain and Cough, Triaminic Softchews Cough & Sore Throat, EQL Severe Cold, GNP Day Time D Cold/Flu, PX Daytime Multi-Symptom, RA Acetaminophen Flu Cold

Synonyms: n.a.

Iloprost inhalation

Generic Name: iloprost

Brand name: Ventavis

Synonyms: Iloprost

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.