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Acetaminophen, Dextromethorphan, Doxylamine, and Pseudoephedrine Capsules and Terazosin

Determining the interaction of Acetaminophen, Dextromethorphan, Doxylamine, and Pseudoephedrine Capsules and Terazosin and the possibility of their joint administration.

Check result:
Acetaminophen, Dextromethorphan, Doxylamine, and Pseudoephedrine Capsules <> Terazosin
Relevance: 09.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using terazosin together with pseudoephedrine may cause an increase in blood pressure. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or need your blood pressure checked more often to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Sympathomimetic agents, such as pseudoephedrine, may antagonize the effects of antihypertensives that interfere with sympathetic activity, such as alpha- and beta-adrenergic blocking agents. In contrast, alpha- and beta-blockers may diminish the vasoconstrictive effects of sympathomimetics. The mechanism of this interaction has not been reported, but may involve competitive inhibition at the adrenergic receptor. Severe hypertension may occur in patients receiving beta-blockers.

MANAGEMENT: Caution and close monitoring of blood pressure is recommended if pseudoephedrine is administered with these antihypertensives. Discontinuation of the sympathomimetic may be necessary if hypertension develops.

References
  • Cerner Multum, Inc. "Australian Product Information." O 0
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • "Product Information. Allegra-D (fexofenadine-pseudoephedrine)." Chattem Consumer Products, Chattanooga, TN.
Acetaminophen, Dextromethorphan, Doxylamine, and Pseudoephedrine Capsules

Generic Name: acetaminophen / dextromethorphan / doxylamine / pseudoephedrine

Brand name: NyQuil D, Nyquil Hot Therapy, All-Nite Cold, Nyquil Cold Medicine, Nyquil Liquicap, Robitussin Night Cold, Tylenol Flu Night Time, Alka-Seltzer Plus Night Time Cold Liquigel, Tylenol Severe Cold & Flu Night Time, Night Time, Theraflu Nighttime Severe Cold, All-Nite Multi-Symptom Cold/Flu Relief, Multi-Symptom Nighttime, NyCair

Synonyms: Acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine

Terazosin

Generic Name: terazosin

Brand name: Hytrin

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.