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Acetaminophen, Dextromethorphan, Doxylamine, and Pseudoephedrine Liquid and Digoxin Tablets

Determining the interaction of Acetaminophen, Dextromethorphan, Doxylamine, and Pseudoephedrine Liquid and Digoxin Tablets and the possibility of their joint administration.

Check result:

Acetaminophen, Dextromethorphan, Doxylamine, and Pseudoephedrine Liquid <> Digoxin Tablets

Relevance: 22.06.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using digoxin together with pseudoephedrine may occasionally cause an irregular heart rhythm. Patients with heart disease should generally consult with their doctor before using pseudoephedrine or similar medications, since they can affect heart rate and blood pressure. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: The concomitant use of sympathomimetic agents and cardiac glycosides may increase the risk of cardiac arrhythmias. The mechanism of this interaction is not known. Increased ectopic pacemaker activity has been reported to occur in patients taking digoxin in combination with pseudoephedrine.

MANAGEMENT: Caution should be exercised if these two drugs are coadministered. Electrocardiogram monitoring (ECG) is recommended. The use of epinephrine (adrenaline) with high doses of digitalis glycosides is not recommended.

References

"Product Information. Claritin-D (loratadine-pseudoephedrine)." Schering-Plough, Liberty Corner, NJ.
"Product Information. Allegra-D (fexofenadine-pseudoephedrine)." Chattem Consumer Products, Chattanooga, TN.
"Product Information. Epinephrine Hydrochloride Injection (epinephrine)." Abbott Pharmaceutical, Abbott Park, IL.
"Product Information. Isuprel (isoproterenol)." Sanofi Winthrop Pharmaceuticals, New York, NY.
Cerner Multum, Inc. "Australian Product Information." O 0
Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
"Product Information. Lanoxin (digoxin)." Glaxo Wellcome, Research Triangle Park, NC.

Acetaminophen, Dextromethorphan, Doxylamine, and Pseudoephedrine Liquid

Generic Name: acetaminophen / dextromethorphan / doxylamine / pseudoephedrine

Brand name: NyQuil D, Nyquil Hot Therapy, All-Nite Cold, Nyquil Cold Medicine, Nyquil Liquicap, Robitussin Night Cold, Tylenol Flu Night Time, Alka-Seltzer Plus Night Time Cold Liquigel, Tylenol Severe Cold & Flu Night Time, Night Time, Theraflu Nighttime Severe Cold, All-Nite Multi-Symptom Cold/Flu Relief, Multi-Symptom Nighttime, NyCair

Synonyms: Acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine

What is Acetaminophen, Dextromethorphan, Doxylamine, and Pseudoephedrine Liquid?

Digoxin Tablets

Generic Name: digoxin

Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin

Synonyms: Digoxin

What is Digoxin Tablets?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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