Acetaminophen, Dextromethorphan, Guaifenesin, and Phenylephrine Liquid and Rifadin IV Intravenous
Determining the interaction of Acetaminophen, Dextromethorphan, Guaifenesin, and Phenylephrine Liquid and Rifadin IV Intravenous and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Rifampin may slightly decrease the therapeutic effects of acetaminophen, although at usual doses, no intervention appears to be necessary. Additionally, rifampin may increase the risk of hepatotoxicity in patients taking acetaminophen and isoniazid.
- Nolan CM, Sandblom RE, Thummel KE, Slattery JT, Nelson SD "Hepatotoxicity associated with acetaminophen usage in patients receiving multiple drug therapy for tuberculosis." Chest 105 (1994): 408-11
- Prescott LF, Critchley JA, Balali-Mood M, Pentland B "Effects of microsomal enzyme induction on paracetamol metabolism in man." Br J Clin Pharmacol 12 (1981): 149-53
- Bock KW, Wiltfang J, Blume R, Ullrich D, Bircher J "Paracetamol as a test drug to determine glucuronide formation in man: effects of inducers and of smoking." Eur J Clin Pharmacol 31 (1987): 677-83
Generic Name: acetaminophen / dextromethorphan / guaifenesin / phenylephrine
Brand name: DayQuil Severe Cold & Flu, Delsym Cough Plus Cold Day Time, Mucinex Children's Cold, Cough & Sore Throat, Mucinex Fast-Max Severe Cold, Sudafed PE Cold & Cough, Tylenol Cold & Flu Severe, Tylenol Cold Multi-Symptom Severe, Mucinex Sinus-Max, Sudafed PE Cold/Cough, Tylenol Cold Head Congestion, Tylenol Cold Multi Symptom, Tylenol Cold/Flu Severe, Vicks DayQuil Severe Cold/Flu
Synonyms: Acetaminophen, dextromethorphan, guaifenesin, and phenylephrine
Generic Name: rifampin
Brand name: Rifadin IV, Rifadin, Rimactane
Synonyms: Rifadin IV (Intravenous), Rifadin IV
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Acetaminophen, Dextromethorphan, Guaifenesin, and Phenylephrine Liquid-Rifamate
- Acetaminophen, Dextromethorphan, Guaifenesin, and Phenylephrine Liquid-Rifampin
- Acetaminophen, Dextromethorphan, Guaifenesin, and Phenylephrine Liquid-Rifampin and Isoniazid
- Acetaminophen, Dextromethorphan, Guaifenesin, and Phenylephrine Liquid-Rifampin Capsules
- Acetaminophen, Dextromethorphan, Guaifenesin, and Phenylephrine Liquid-Rifampin Injection
- Acetaminophen, Dextromethorphan, Guaifenesin, and Phenylephrine Liquid-Rifampin Intravenous
- Rifadin IV Intravenous-Acetaminophen, dextromethorphan, guaifenesin, and pseudoephedrine
- Rifadin IV Intravenous-Acetaminophen, Dextromethorphan, Guaifenesin, and Pseudoephedrine Liquid
- Rifadin IV Intravenous-Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine Caps & Tabs
- Rifadin IV Intravenous-Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine Caps & Tabs
- Rifadin IV Intravenous-Acetaminophen, Dextromethorphan, Phenylephrine, and Diphenhydramine
- Rifadin IV Intravenous-Acetaminophen, dextromethorphan, pseudoephedrine, and pyrilamine