Acetaminophen, Dextromethorphan, Guaifenesin, and Pseudoephedrine Liquid and Hyoscyamine Sulfate Sublingual Tablet
Determining the interaction of Acetaminophen, Dextromethorphan, Guaifenesin, and Pseudoephedrine Liquid and Hyoscyamine Sulfate Sublingual Tablet and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Anticholinergic agents may delay and/or decrease the gastrointestinal absorption of acetaminophen by reducing gastric motility and delaying gastric emptying. However, the clinical relevance is probably minimal.
- Clark JM, Seager SJ "Gastric emptying following premedication with glycopyrrolate or atropine." Br J Anaesth 55 (1983): 1195-9
- "Product Information. Transderm Scop (scopolamine)." Ciba Self-Medication Inc, Woodbridge, NJ.
- Nimmo J, Heading RC, Tothill P, Prescott LF "Pharmacological modification of gastric emptying: effects of propantheline and metoclopramide on paracetamol absorption." Br Med J 1 (1973): 587-9
Generic Name: acetaminophen / dextromethorphan / guaifenesin / pseudoephedrine
Brand name: Duraflu, Robitussin Cold Cough and Flu, Theraflu Max-D Severe Cold & Flu, Sudafed Cold and Cough Liquicaps, Theraflu Chest and Cough, Tylenol Cold Severe Congestion Non-Drowsy, Sudafed Sinus and Cold Liquicaps, Phlemgesic, Maxiflu DM, Flutabs, Tylenol Cold Severe Congestion
Synonyms: Acetaminophen, dextromethorphan, guaifenesin, and pseudoephedrine
Generic Name: hyoscyamine
Brand name: Anaspaz, Ed Spaz, Hyosyne, Levbid, Levsin, NuLev, Symax SR, Cystospaz, Levsin SL, Cystospaz-M, Levsinex SR, Symax SL, A-Spas S/L, Donnamar, Hyosol, NuLev, Spasdel, IB-Stat, Hyospaz, Symax Duotab, Symax FasTab, HyoMax SL, HyoMax SR, HyoMax FT, HyoMax DT, HyoMax, Oscimin, A-Spaz, Levsin/SL, Colidrops, Levsinex, Symax, Symax FasTabs
Synonyms: Hyoscyamine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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