Acetaminophen/Dextromethorphan/Guaifenesin/Pseudoephedrine Powder Packs and Digoxin Tablets
Determining the interaction of Acetaminophen/Dextromethorphan/Guaifenesin/Pseudoephedrine Powder Packs and Digoxin Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using digoxin together with pseudoephedrine may occasionally cause an irregular heart rhythm. Patients with heart disease should generally consult with their doctor before using pseudoephedrine or similar medications, since they can affect heart rate and blood pressure. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The concomitant use of sympathomimetic agents and cardiac glycosides may increase the risk of cardiac arrhythmias. The mechanism of this interaction is not known. Increased ectopic pacemaker activity has been reported to occur in patients taking digoxin in combination with pseudoephedrine.
MANAGEMENT: Caution should be exercised if these two drugs are coadministered. Electrocardiogram monitoring (ECG) is recommended. The use of epinephrine (adrenaline) with high doses of digitalis glycosides is not recommended.
- "Product Information. Claritin-D (loratadine-pseudoephedrine)." Schering-Plough, Liberty Corner, NJ.
- "Product Information. Allegra-D (fexofenadine-pseudoephedrine)." Chattem Consumer Products, Chattanooga, TN.
- "Product Information. Epinephrine Hydrochloride Injection (epinephrine)." Abbott Pharmaceutical, Abbott Park, IL.
- "Product Information. Isuprel (isoproterenol)." Sanofi Winthrop Pharmaceuticals, New York, NY.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Lanoxin (digoxin)." Glaxo Wellcome, Research Triangle Park, NC.
Generic Name: acetaminophen / dextromethorphan / guaifenesin / pseudoephedrine
Brand name: Duraflu, Robitussin Cold Cough and Flu, Theraflu Max-D Severe Cold & Flu, Sudafed Cold and Cough Liquicaps, Theraflu Chest and Cough, Tylenol Cold Severe Congestion Non-Drowsy, Sudafed Sinus and Cold Liquicaps, Phlemgesic, Maxiflu DM, Flutabs, Tylenol Cold Severe Congestion
Synonyms: Acetaminophen, dextromethorphan, guaifenesin, and pseudoephedrine
Generic Name: digoxin
Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin
Synonyms: Digoxin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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- Acetaminophen/Dextromethorphan/Guaifenesin/Pseudoephedrine Powder Packs-Dihydrocodeine, Aspirin, and Caffeine
- Acetaminophen/Dextromethorphan/Guaifenesin/Pseudoephedrine Powder Packs-Dihydroergotamine
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- Digoxin Tablets-Acetazolamide
- Digoxin Tablets-Acetazolamide Capsules
- Digoxin Tablets-Acetazolamide Injection Solution
- Digoxin Tablets-Acetazolamide Sodium
- Digoxin Tablets-Acetazolamide Sustained-Release Capsules
- Digoxin Tablets-Acetazolamide Tablets