Acetaminophen, dextromethorphan, pseudoephedrine, and pyrilamine and Bavencio

• Generic Name: acetaminophen / dextromethorphan / pseudoephedrine / pyrilamine
• Dosage Forms: n.a.
• Other Brand Names: Robitussin Night Relief

Acetaminophen is a pain reliever and fever reducer.

Dextromethorphan is a cough suppressant. It affects the cough reflex in the brain that triggers coughing.

Pyrilamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Acetaminophen, dextromethorphan, pseudoephedrine, and pyrilamine is a combination medicine used to treat headache, fever, body aches, cough, runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.

acetaminophen, dextromethorphan, pseudoephedrine, and pyrilamine will not treat a cough that is caused by smoking, asthma, or emphysema.

Acetaminophen, dextromethorphan, pseudoephedrine, and pyrilamine may also be used for purposes not listed in this medication guide.

• Generic Name: avelumab
• Dosage Forms: injection, solution, concentrate
• Other Brand Names: Bavencio

Bavencio (avelumab) is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Bavencio is used to treat a type of skin cancer called Merkel cell carcinoma (MCC) in adults and children at least 12 years old, when the cancer has spread to other parts of the body (metastatic).

Bavencio was approved for MCC by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, tumors responded to this medicine. However, further studies are needed.

Bavencio is used to treat a certain type of cancer of the bladder or urinary tract that has spread or cannot be removed with surgery. Avelumab is given for this condition after platinum cancer medicines did not work or have stopped working.

Bavencio is also used used alone or in combination with the medicine axitinib for the treatment of a type of kidney cancer called renal cell carcinoma (RCC) that has spread or cannot be removed by surgery (advanced RCC).