Acetaminophen, Isometheptene, and Dichloralphenazone and Bromocriptine Capsules
Determining the interaction of Acetaminophen, Isometheptene, and Dichloralphenazone and Bromocriptine Capsules and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ask your doctor before using bromocriptine together with isometheptene mucate. Using these medications together may increase the adverse effects of bromocriptine. This may cause low blood pressure, which can lead to dizziness and other symptoms, especially when you rise from a sitting or lying position. Also use caution when driving or performing other hazardous activities. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Several case reports suggest that some sympathomimetics, including phenylpropanolamine and isometheptene, may worsen the side effects of bromocriptine. The mechanism is unknown, but may be due to additive pharmacodynamic effects. Hypertension, ventricular tachycardia, headaches, and seizures have been reported when phenylpropanolamine or isometheptene has been used in combination with bromocriptine.
MANAGEMENT: Until more information is available, the concurrent use of these agents should be avoided.
- Kulig K, Moore LL, Kirk M, Smith D, Stallworth J, Rumack B "Bromocriptine-associated headache: possible life-threatening sympathomimetic interaction." Obstet Gynecol 78 (1991): 941-3
- Gittelman DK "Bromocriptine associated with postpartum hypertension, seizures, and pituitary hemorrhage." Gen Hosp Psychiatry 13 (1991): 278-80
Generic Name: acetaminophen / dichloralphenazone / isometheptene mucate
Brand name: Nodolor
Synonyms: n.a.
Generic Name: bromocriptine
Brand name: Parlodel, Cycloset
Synonyms: Bromocriptine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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