Acetazolamide Injection Solution and Amitriptyline Hydrochloride
Determining the interaction of Acetazolamide Injection Solution and Amitriptyline Hydrochloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Acetazolamide may decrease urinary excretion of tricyclic antidepressants by alkalinizing the urine. This interaction is unlikely to be clinically important.
- Gram LF, Kofod B, Christiansen J, Rafaelsen OJ "Imipramine metabolism: pH-dependent distribution and urinary excretion." Clin Pharmacol Ther 12 (1971): 239-44
Generic Name: acetazolamide
Brand name: Diamox, Diamox Sequels
Synonyms: Acetazolamide, AcetaZOLAMIDE
Generic Name: amitriptyline
Brand name: Vanatrip, Elavil, Endep
Synonyms: Amitriptyline
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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