Acetazolamide Injection Solution and Vecuronium
Determining the interaction of Acetazolamide Injection Solution and Vecuronium and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Before you undergo any procedure where acetaZOLAMIDE may be used, let your doctor know if you are currently using vecuronium or other diuretics. Diuretics can cause potassium loss and prolong the effects of vecuronium. You should be closely monitored by the doctor during the procedure, and the dosage of vecuronium adjusted as necessary. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Diuretics may induce hypokalemia and prolong the neuromuscular blocking effects of nondepolarizing muscle relaxants.
MANAGEMENT: Close monitoring for prolonged neuromuscular blockade, potassium replacement when indicated, and neuromuscular blocker dose adjustment is recommended.
- Agencia EspaƱola de Medicamentos y Productos Sanitarios Healthcare "Centro de informaciĆ³n online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]):
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. HydroDIURIL (hydrochlorothiazide)." Merck & Co, Inc, West Point, PA.
- Miller RD, Roderick LL "Diuretic-induced hypokalemia, pancuronium neuromuscular blockade and its antagonism by neostigmine." Br J Anaesth 50 (1978): 541-4
Generic Name: acetazolamide
Brand name: Diamox, Diamox Sequels
Synonyms: Acetazolamide, AcetaZOLAMIDE
Generic Name: vecuronium
Brand name: Vecuronium Bromide, Norcuron
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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