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Acetazolamide Tablets and Amitriptyline

Determining the interaction of Acetazolamide Tablets and Amitriptyline and the possibility of their joint administration.

Check result:

Acetazolamide Tablets <> Amitriptyline

Relevance: 01.10.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Acetazolamide may decrease urinary excretion of tricyclic antidepressants by alkalinizing the urine. This interaction is unlikely to be clinically important.

References

Gram LF, Kofod B, Christiansen J, Rafaelsen OJ "Imipramine metabolism: pH-dependent distribution and urinary excretion." Clin Pharmacol Ther 12 (1971): 239-44

Acetazolamide Tablets

Generic Name: acetazolamide

Brand name: Diamox, Diamox Sequels

Synonyms: Acetazolamide, AcetaZOLAMIDE

What is Acetazolamide Tablets?

Amitriptyline

Generic Name: amitriptyline

Brand name: Vanatrip, Elavil, Endep

Synonyms: n.a.

What is Amitriptyline?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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