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Acetazolamide Tablets and Azopt 1%

Determining the interaction of Acetazolamide Tablets and Azopt 1% and the possibility of their joint administration.

Check result:
Acetazolamide Tablets <> Azopt 1%
Relevance: 01.10.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Talk to your doctor before using brinzolamide ophthalmic together with acetaZOLAMIDE. After brinzolamide ophthalmic is instilled into the eye, the medication can be absorbed into the bloodstream and cause some of the same effects as acetaZOLAMIDE. This can increase the risk and/or severity of side effects like drowsiness, dizziness, numbness or tingling in the hands and feet, ringing in the ears, loss of appetite, nausea, vomiting, and diarrhea. If your doctor does prescribe these medications together, you may need a dose adjustment or regular blood tests to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Following ophthalmic administration, brinzolamide and dorzolamide are systemically absorbed and may have additive pharmacologic effects with other, systemically administered carbonic anhydrase inhibitors. The risk of adverse effects such as drowsiness, paresthesia, tinnitus, electrolyte imbalance, metabolic acidosis, and gastrointestinal disturbances may be increased.

MANAGEMENT: The concomitant use of ocular and systemic carbonic anhydrase inhibitors is not recommended.

References
  • "Product Information. Azopt (brinzolamide ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.
  • "Product Information. Trusopt (dorzolamide ophthalmic)." Merck & Co, Inc, West Point, PA.
Acetazolamide Tablets

Generic Name: acetazolamide

Brand name: Diamox, Diamox Sequels

Synonyms: Acetazolamide, AcetaZOLAMIDE

Azopt 1%

Generic Name: brinzolamide ophthalmic

Brand name: Azopt

Synonyms: Azopt

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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