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Acetazolamide Tablets and Dolobid

Determining the interaction of Acetazolamide Tablets and Dolobid and the possibility of their joint administration.

Check result:
Acetazolamide Tablets <> Dolobid
Relevance: 01.10.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Diflunisal may significantly increase the plasma concentrations of carbonic anhydrase inhibitors (CAIs). Data suggest that diflunisal decreases the renal excretion of CAIs. Diflunisal has been used to augment the ocular hypotensive effect of acetazolamide.

References
  • Yablonski ME, Maren TH, Hayashi M, Naveh N, Potash SD, Pessah N "Enhancement of the ocular hypotensive effect of acetazolamide by diflunisal." Am J Ophthalmol 106 (1988): 332-6
Acetazolamide Tablets

Generic Name: acetazolamide

Brand name: Diamox, Diamox Sequels

Synonyms: Acetazolamide, AcetaZOLAMIDE

Dolobid

Generic Name: diflunisal

Brand name: Dolobid

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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