Acid Controller Original Strength and Nicorelief gum, lozenge
Determining the interaction of Acid Controller Original Strength and Nicorelief gum, lozenge and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:H2 antagonists may reduce the clearance of nicotine. Cimetidine, 600 mg given twice a day for two days, reduced clearance of an intravenous nicotine dose by 30%. Ranitidine, 300 mg given twice a day for two days, reduced clearance by 10%. The clinical significance of this interaction is not known. Patients should be monitored for increased nicotine effects when using the patches or gum for smoking cessation and dosage adjustments should be made as appropriate.
- Bendayan R, Sullivan JT, Shaw C, Frecker RC, Sellers EM "Effect of cimetidine and ranitidine on the hepatic and renal elimination of nicotine in humans." Eur J Clin Pharmacol 38 (1990): 165-9
Generic Name: famotidine
Brand name: Pepcid, Heartburn Relief, Pepcid AC, Pepcid AC Maximum Strength, Pepcid AC Chewable Tablets, Pepcid Oral Suspension
Synonyms: n.a.
Generic Name: nicotine
Brand name: Leader Nicotine Polacrilex, Nicorelief, Nicorette, Thrive, Commit, Habitrol, Nicoderm C-Q, Nicotine System Kit, Nicoderm CQ, Nicotrol Inhaler, Nicotrol NS
Synonyms: Nicorelief (gum, lozenge)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Acid Controller Original Strength-Nicorette
- Acid Controller Original Strength-Nicorette Drugs Facts
- Acid Controller Original Strength-Nicorette Fruit Chill
- Acid Controller Original Strength-Nicorette Inhaler
- Acid Controller Original Strength-Nicorette White Ice
- Acid Controller Original Strength-Nicotine
- Nicorelief gum, lozenge-Acid Gone
- Nicorelief gum, lozenge-Acid Reducer
- Nicorelief gum, lozenge-Acid Relief
- Nicorelief gum, lozenge-Aciphex
- Nicorelief gum, lozenge-Aciphex (Rabeprazole Delayed-Release Tablets)
- Nicorelief gum, lozenge-Aciphex (Rabeprazole Sprinkle Capsules)