Acitretin and Tolazamide

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using TOLAZamide together with acitretin may alter your blood sugar levels. You should be advised to regularly monitor your blood sugar and counseled on how to recognize and treat hypoglycemia (low blood sugar), which may include symptoms such as headache, dizziness, drowsiness, nervousness, confusion, tremor, hunger, weakness, perspiration, and palpitations. You may need a dose adjustment or blood sugar checked more often to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Acitretin in the presence of sulfonylureas may lead to enhanced clearance of blood glucose. The mechanism and the clinical significance of this interaction are unknown. In addition, increases and decreases in fasting blood glucose have been reported with acitretin alone.

MANAGEMENT: The manufacturer of acitretin recommends that diabetic patients be observed closely for altered blood glucose levels. Patients should be advised to regularly monitor their blood sugar, counseled on how to recognize and treat hypoglycemia (e.g., headache, dizziness, drowsiness, nausea, tremor, hunger, weakness, or palpitations), and to notify their physician if loss of glycemic control occurs.

Acitretin

Generic Name: acitretin

Brand name: Soriatane, Soriatane CK

Synonyms: n.a.

What is Acitretin?

Tolazamide

Generic Name: tolazamide

Brand name: Tolinase

Synonyms: TOLAZamide

What is Tolazamide?