Aclasta and Activase

• Generic Name: zoledronic acid
• Dosage Forms: n.a.
• Other Brand Names: Aclasta, Zometa, Reclast, Zometa Concentrate

Aclasta contains zoledronic acid (sometimes called zoledronate). It belongs to a group of medicines called bisphosphonates. Zoledronic acid inhibits the release of calcium from bones.

Aclasta is used to treats Paget's disease and osteoporosis in postmenopausal women.

Aclasta may also be used for other purposes not listed in this medication guide.

• Generic Name: alteplase
• Dosage Forms: injection
• Other Brand Names: Activase, Cathflo Activase

Activase is a thrombolytic (THROM-bo-LIT-ik) drug, sometimes called a "clot-busting" drug. It helps your body produce a substance that dissolves unwanted blood clots.

Activase is used to treat a stroke caused by a blood clot or other obstruction in a blood vessel. This medicine is also used to prevent death from a heart attack (acute myocardial infarction).

Activase is also used to treat a blood clot in the lung (pulmonary embolism).

Activase is also used to dissolve blood clots that have formed in or around a catheter placed inside a blood vessel. This improve the flow of medicines injected in through the catheter, or blood drawn out through the catheter.

Activase may also be used for purposes not listed in this medication guide.