Actemra (Tocilizumab Auto-Injectors) and Adalimumab Vials

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using tocilizumab together with adalimumab may increase the risk of serious and potentially life-threatening infections. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. Contact your doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: Coadministration of interleukin-6 (IL-6) inhibitors with other biologic disease-modifying antirheumatic drugs (DMARDs) may result in increased immunosuppression and a greater risk of infection. Treatment with IL-6 inhibitors has been associated with serious, potentially life-threatening and fatal infections, including tuberculosis, invasive fungal infections such as candidiasis, aspergillosis and pneumocystis, and other opportunistic infections. Cases have occurred mostly in patients receiving concomitant immunosuppressants like methotrexate or corticosteroids. Use of IL-6 inhibitors in combination with biologic DMARDs such as tumor necrosis factor (TNF) blockers, IL-1R antagonists, anti-CD20 monoclonal antibodies, or T-cell costimulation modulators has not been studied. There may be an increased risk of neutropenia and infections during treatment with IL-6 inhibitors in patients who were previously exposed to TNF antagonists.

MANAGEMENT: Concomitant use of IL-6 inhibitors with other biologic DMARDs should be avoided.

Actemra (Tocilizumab Auto-Injectors)

Generic Name: tocilizumab

Brand name: Actemra, Actemra ACTPen

Synonyms: Actemra

What is Actemra (Tocilizumab Auto-Injectors)?

Adalimumab Vials

Generic Name: adalimumab

Brand name: Humira, Humira Pen, Humira Pen Crohns/UlcerColit/HidraSuppur, Humira Pen Psoriasis/Uveitis Starter Package, Humira Pediatric, Humira Pediatric Crohn's Disease Starter Pack, Humira Pre-Filled Syringe, Humira Pen Psoriasis/Uveitis/Adol HidraSuppur Starter Pack, Humira Pen Crohns/Ulcer Colitis/Hidradenitis Suppurati StrPk

Synonyms: Adalimumab

What is Adalimumab Vials?