Acthar and FluMist 2018-2019 nasal

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

If you are currently being treated or have recently been treated with corticotropin, you should talk to your doctor before receiving influenza virus vaccine, live. Depending on the dose and length of time you have been on corticotropin, you may be at risk for developing an infection from the vaccine or have a reduced response to the vaccine. In some situations, your doctor may want to delay vaccination to give your body time to recover from the effects of corticotropin therapy. If you have recently been vaccinated with influenza virus vaccine, live, your doctor may choose to postpone treatment with corticotropin for a couple of weeks. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: The administration of live, attenuated virus or bacterial vaccines during corticosteroid therapy may be associated with a risk of disseminated infection due to enhanced replication of vaccine virus or bacteria in the presence of diminished immune competence. Patients may be immunosuppressed if they have recently received or are receiving high dosages of corticosteroids or adrenocorticotropic agents (e.g., greater than 10 mg/day or 1 mg/kg/day of prednisone or equivalent for more than 2 weeks), or long-term topical or inhaled corticosteroids. Such patients may also have increased adverse reactions and decreased or suboptimal immunologic response to vaccines. With respect to chronic corticosteroid inhalation therapy, a study was conducted to examine immune responsiveness to varicella vaccine in pediatric asthma patients ages 12 months to 8 years treated with budesonide inhalation suspension 0.25 mg to 1 mg daily. Compared to patients on noncorticosteroid asthma therapy, there was no significant difference in the percentage of budesonide patients who developed a seroprotective antibody titer following vaccination (85% vs. 90% for noncorticosteroid). In addition, no patient treated with budesonide inhalation suspension developed chicken pox as a result of vaccination.

MANAGEMENT: In general, live attenuated vaccines should not be used in patients receiving immunosuppressive corticosteroid therapy. Vaccination should be deferred until after such therapy is discontinued and immune function has been restored. The interval depends on the dosage and duration of corticosteroid therapy administered, but may be at least 3 months in most cases. Current local immunization guidelines should be consulted for recommendations. In patients who have recently been vaccinated, high-dose corticosteroid therapy should not be initiated for at least 2 weeks. Vaccines may generally be administered to patients receiving corticosteroids as replacement therapy (e.g., for Addison's disease).

Acthar

Generic Name: corticotropin

Brand name: Acthar, Acthar Gel, HP, ACTH Gel, ACTH-80, ACTH-40 HP

Synonyms: n.a.

What is Acthar?

FluMist 2018-2019 nasal

Generic Name: influenza virus vaccine, live, trivalent

Brand name: FluMist 2018-2019, FluMist Quadrivalent, Flumist, FluMist 2010-2011, FluMist 2011-2012, FluMist 2012-2013, FluMist 2013-2014, FluMist 2014-2015, FluMist 2015-2016, FluMist 2016-2017, FluMist Quadrivalent 2019-2020

Synonyms: FluMist Nasal Spray, Flumist

What is FluMist 2018-2019 nasal?