Actigall and Collagenase clostridium histolyticum

• Generic Name: ursodiol
• Dosage Forms: capsule
• Other Brand Names: Actigall, Urso, Urso Forte, Urso DS

Actigall is a bile acid that decreases the amount of cholesterol produced by the liver and absorbed by the intestines. This medicine helps break down cholesterol that has formed into stones in the gallbladder. This medicine also increases bile flow in patients with primary biliary cirrhosis.

Actigall is used to treat primary biliary cirrhosis.

Actigall capsules are used to treat small gallstones in people who cannot have gallbladder surgery, and to prevent gallstones in overweight patients undergoing rapid weight loss. This medicine capsules are not for treating gallstones that are calcified.

Actigall may also be used for purposes not listed in this medication guide.

• Generic Name: collagenase clostridium histolyticum
• Dosage Forms: n.a.
• Other Brand Names: Xiaflex

Collagenase clostridium histolyticum is made from a mixture of proteins derived from a certain bacteria.

Collagenase clostridium histolyticum is used to treat Dupuytren's contracture in adults. This condition causes an abnormal thickening of the tissue in the palm of the hand. This condition may get worse over time and form a "cord" in your palm, causing a permanent bend in your finger.

Collagenase clostridium histolyticum is also used to treat a related condition called Peyronie's disease in adult men. This condition causes scar tissue or "plaque" to develop under the skin of the penis, resulting in an abnormal curving of the penis during erection.

Collagenase clostridium histolyticum is available for Peyronie's disease only from a certified pharmacy under a special program called Xiaflex REMS. You must be registered in the program and understand the risks of taking collagenase clostridium histolyticum.

Collagenase clostridium histolyticum may also be used for purposes not listed in this medication guide.