Activase and Cetiri D

• Generic Name: alteplase
• Dosage Forms: injection
• Other Brand Names: Activase, Cathflo Activase

Activase is a thrombolytic (THROM-bo-LIT-ik) drug, sometimes called a "clot-busting" drug. It helps your body produce a substance that dissolves unwanted blood clots.

Activase is used to treat a stroke caused by a blood clot or other obstruction in a blood vessel. This medicine is also used to prevent death from a heart attack (acute myocardial infarction).

Activase is also used to treat a blood clot in the lung (pulmonary embolism).

Activase is also used to dissolve blood clots that have formed in or around a catheter placed inside a blood vessel. This improve the flow of medicines injected in through the catheter, or blood drawn out through the catheter.

Activase may also be used for purposes not listed in this medication guide.

• Generic Name: cetirizine / pseudoephedrine
• Dosage Forms: tablet, extended release
• Other Brand Names: All Day Allergy-D, Goodsense Cetirizine D-12 Hour, Zyrtec-D, KS Aller-Tec D-12, Wal-Zyr D, Allergy D-12, Allergy Relief Nasal Decongestant, Leader Allergy Relief D

Hydrocodone and acetaminophen combination is used to relieve pain severe enough to require opioid treatment and when other pain medicines did not work well enough or cannot be tolerated.

Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses, including liver damage.

Hydrocodone belongs to the group of medicines called narcotic analgesics (pain medicines). It acts on the central nervous system (CNS) to relieve pain, and stops or prevents cough.

When hydrocodone is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.

This medicine is available only under a restricted distribution program called the Opioid Analgesic REMS (Risk Evaluation and Mitigation Strategy) program.