Activase and Deoxycholic acid
Determining the interaction of Activase and Deoxycholic acid and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Treatment with alteplase may increase the risk of bruising in areas where deoxycholic acid has been injected. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with agents that alter hemostasis such as anticoagulants, platelet inhibitors, thrombin inhibitors, thrombolytics, or agents that commonly cause thrombocytopenia may increase the risk of submental hematoma or bruising in association with deoxycholic acid administration. In clinical trials, 72% of subjects treated with deoxycholic acid experienced injection site hematoma or bruising.
MANAGEMENT: Deoxycholic acid should be used with caution in patients receiving drugs that may interfere with hemostasis.
- "Product Information. Kybella (deoxycholic acid)." Kythera Biopharmaceuticals, Inc., Westlake Village, CA.
Generic Name: alteplase
Brand name: Activase, Cathflo Activase
Synonyms: n.a.
Generic Name: deoxycholic acid
Brand name: Kybella
Synonyms: Deoxycholic Acid
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Activase-Deoxycholic acid Subcutaneous
- Activase-Depacon
- Activase-Depade
- Activase-Depakene
- Activase-Depakene (Valproic Acid Capsules)
- Activase-Depakene (Valproic Acid Liquid)
- Deoxycholic acid-Activated Charcoal
- Deoxycholic acid-Activated Charcoal Capsules and Tablets
- Deoxycholic acid-Activated Charcoal Liquid
- Deoxycholic acid-Active FE
- Deoxycholic acid-Active OB
- Deoxycholic acid-Activella