Activella Oral and Butrans Patch

• Generic Name: estradiol / norethindrone
• Dosage Forms: tablet, film coated
• Other Brand Names: Activella, Mimvey, CombiPatch

Estradiol and norethindrone combination is used to treat moderate to severe hot flashes and other symptoms of menopause. It is also used to treat changes in and around the vagina (such as vaginal dryness, itching, and burning) caused by low estrogen levels or menopause. This medicine is also used to treat certain conditions in women before menopause if their ovaries do not make enough estrogens naturally, and prevent osteoporosis after menopause.

This medicine is a combination of two hormones: an estrogen hormone (estradiol) and a progestin hormone (norethindrone). It works by preventing symptoms, such as feelings of warmth in the face, neck, and chest, or sudden strong feelings of heat and sweating (hot flashes) in women during menopause.

This medicine is available only with your doctor's prescription.

• Generic Name: buprenorphine
• Dosage Forms: patch, extended release
• Other Brand Names: Butrans, Belbuca, Buprenex, Probuphine, Sublocade, Subutex

Butrans skin patches contain buprenorphine, an opioid pain medication. An opioid is sometimes called a narcotic.

Butrans skin patches are used for around-the-clock treatment of moderate to severe chronic pain that is not controlled by other medicines.

Butrans is not for use on an as-needed basis for pain.