Activella Oral and Somavert

• Generic Name: estradiol / norethindrone
• Dosage Forms: tablet, film coated
• Other Brand Names: Activella, Mimvey, CombiPatch

Estradiol and norethindrone combination is used to treat moderate to severe hot flashes and other symptoms of menopause. It is also used to treat changes in and around the vagina (such as vaginal dryness, itching, and burning) caused by low estrogen levels or menopause. This medicine is also used to treat certain conditions in women before menopause if their ovaries do not make enough estrogens naturally, and prevent osteoporosis after menopause.

This medicine is a combination of two hormones: an estrogen hormone (estradiol) and a progestin hormone (norethindrone). It works by preventing symptoms, such as feelings of warmth in the face, neck, and chest, or sudden strong feelings of heat and sweating (hot flashes) in women during menopause.

This medicine is available only with your doctor's prescription.

• Generic Name: pegvisomant
• Dosage Forms: subcutaneous injection
• Other Brand Names: Somavert

Somavert (pegvisomant) is a man-made protein that is similar to human growth hormone. Pegvisomant binds to the same receptor in the body as growth hormone, and blocks the effects of growth hormone.

Somavert is used to treat acromegaly (a growth disorder caused by too much growth hormone).

Somavert is usually given after other medications, surgery, or radiation have been tried without successful treatment of symptoms.