Actoplus Met XR and Adempas

• Generic Name: metformin / pioglitazone
• Dosage Forms: tablet, film coated, extended release
• Other Brand Names: Actoplus Met, Actoplus Met XR

Actoplus Met XR is a combination of two oral diabetes medicines that help control blood sugar levels.

Actoplus Met XR is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus who do not use daily insulin injections. This medicine is not for treating type 1 diabetes.

Actoplus Met XR may also be used for purposes not listed in this medication guide.

• Generic Name: riociguat
• Dosage Forms: n.a.
• Other Brand Names: Adempas

Adempas (riociguat) lowers blood pressure in your lungs, helping your heart pump blood more efficiently.

Adempas is used to treat chronic thromboembolic pulmonary hypertension (CTEPH) in people who cannot be treated with surgery, or in people who have undergone surgery but still have symptoms. Riociguat can treat certain symptoms of CTEPH and can improve your ability to exercise.

Adempas is also used to treat pulmonary arterial hypertension (PAH). Riociguat can improve your ability to exercise and help prevent PAH from getting worse.

Adempas is available to women only under a special program. You must be registered in the program and understand the risks and benefits of this medicine.