Actos and Kaletra

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using ritonavir together with pioglitazone can alter the effects of pioglitazone, which can lead to loss of blood sugar control. Talk with your doctor before using ritonavir while you are using pioglitazone. You may need a dose adjustment and you may need to check your blood sugar more often. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Pioglitazone is a substrate of the hepatic isoenzyme CYP450 3A4. Clinicians should be aware of the potential for an interaction when pioglitazone is used in combination with another medication that is metabolized by and also induces CYP450 3A4.

MANAGEMENT: Patients should be observed for clinical and laboratory evidence of altered safety and efficacy of both drugs if pioglitazone is added to or removed from the patient's medication regimen. Patients should be advised to report loss of blood sugar control to their physician.

Actos

Generic Name: pioglitazone

Brand name: Actos

Synonyms: n.a.

What is Actos?

Kaletra

Generic Name: lopinavir / ritonavir

Brand name: Kaletra

Synonyms: n.a.

What is Kaletra?