Acular eent and Hydroxyprogesterone Caproate

• Generic Name: ketorolac ophthalmic
• Dosage Forms: ophthalmic solution
• Other Brand Names: Acular, Acular LS, Acuvail, Acular PF

Temporary relief of ocular itching due to seasonal allergic (hay fever, pollinosis) conjunctivitis.

Management of postoperative inflammation associated with cataract extraction.

Reduction of ocular pain and burning/stinging following corneal refractive surgery and photorefractive keratectomy (PRK).

Ketorolac tromethamine 0.5% preservative-free ophthalmic solution is used for the reduction of ocular pain and photophobia following incisional refractive surgery.

Treatment, with or without concomitant topical corticosteroid therapy, to prevent or relieve postoperative cystoid macular edema associated with cataract extraction.

Has been used for the active treatment of chronic aphakic or pseudophakic cystoid macular edema.

Has been used prophylactically before ocular surgery to prevent or reduce intraoperative miosis.

• Generic Name: hydroxyprogesterone
• Dosage Forms: n.a.
• Other Brand Names: Makena, Makena Auto-Injector, Hylutin, Delta-Lutin, Duralutin, Hyprogesterone, Prodrox

Reduction of risk of preterm birth in women with a singleton pregnancy having a history of singleton spontaneous preterm birth (designated an orphan drug by FDA for this use).

Efficacy determined based on improvement in proportion of women who delivered at <37 weeks of gestation; direct clinical benefit (e.g., improvement in neonatal morbidity and mortality) not established.

Safety and efficacy demonstrated only in women with a prior spontaneous singleton birth; not intended for use in women with multiple gestations or other risk factors for preterm birth.

ACOG recommends offering progesterone supplementation for prevention of recurrent preterm birth to women with a singleton pregnancy and a prior spontaneous preterm birth at <37 weeks of gestation due to spontaneous preterm labor or premature rupture of membranes.