Acular LS and Vioxx

• Generic Name: ketorolac ophthalmic
• Dosage Forms: ophthalmic solution
• Other Brand Names: Acular, Acular LS, Acuvail, Acular PF

Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body.

Acular LS (for the eye) is used to relieve eye itching caused by seasonal allergies.

Acular LS is also used to reduce swelling, pain, and burning or stinging after cataract surgery or corneal refractive surgery.

Acular LS may also be used for purposes not listed in this medication guide.

• Generic Name: rofecoxib
• Dosage Forms: n.a.
• Other Brand Names: Vioxx

Vioxx was withdrawn from the U.S. market in 2004.

The manufacturer of Vioxx has announced a voluntary withdrawal of the drug from the U.S. and worldwide market. This withdrawal is due to safety concerns of an increased risk of cardiovascular events (including heart attack and stroke) in patients taking Vioxx.

Notify your doctor immediately if you develop abdominal pain, tenderness, or discomfort; nausea; blood in your vomit; bloody, black, or tarry stools; unexplained weight gain; swelling or water retention; fatigue or lethargy; a skin rash; itching; yellowing of your skin or eyes;"flu-like" symptoms; or unusual bruising or bleeding. These symptoms could be early signs of dangerous side effects.