Drug search by name

Acunivive 90 Injection System and Probenecid Tablets

Determining the interaction of Acunivive 90 Injection System and Probenecid Tablets and the possibility of their joint administration.

Check result:

Acunivive 90 Injection System <> Probenecid Tablets

Relevance: 11.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using probenecid and ketorolac is not recommended. Taking these drugs together can cause symptoms of dizziness, excessive drowsiness, decreased urination, or blood in your urine or stools. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

CONTRAINDICATED: The concomitant administration of probenecid and ketorolac may cause ketorolac toxicity. Probenecid decreases the plasma clearance of ketorolac, resulting in a three-fold increase in ketorolac AUC and a two-fold increase in its half-life. Renal failure, GI ulcerations or perforation, and hemorrhage may occur.

MANAGEMENT: The manufacturer considers the concurrent use of probenecid and ketorolac contraindicated.

References

Cerner Multum, Inc. "Australian Product Information." O 0
Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
"Product Information. Toradol (ketorolac)." Roche Laboratories, Nutley, NJ.

Acunivive 90 Injection System

Generic Name: ketorolac

Brand name: Sprix, Toradol

Synonyms: Ketorolac (nasal), Ketorolac (Nasal)

What is Acunivive 90 Injection System?

Probenecid Tablets

Generic Name: probenecid

Brand name: Benemid

Synonyms: Probenecid

What is Probenecid Tablets?

+ Add a drug Remove all

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

The list of popular interactions