Acyclovir (Systemic) and Aminophylline Tablets
Determining the interaction of Acyclovir (Systemic) and Aminophylline Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Limited data suggest that the combination of a methyl xanthine with acyclovir may lead to elevated theophylline levels potentiating pharmacologic and adverse effects. The mechanism may be due to inhibition of theophylline oxidative metabolism. Clinical and laboratory monitoring is warranted if these agents are given concurrently. Patients receiving this combination should be advised to report any signs of theophylline toxicity including nausea, vomiting, diarrhea, headache, restlessness, insomnia, or irregular heartbeat to their physician.
- Maeda Y, Konishi T, Omoda K, Takeda Y, Fukuhara S, Fukuzawa M, Ohune T, Tsuya T, Tsukiai S "Inhibition of theophylline metabolism by aciclovir." Biol Pharm Bull 19 (1996): 1591-5
Generic Name: acyclovir
Brand name: Sitavig, Zovirax
Synonyms: Acyclovir
Generic Name: aminophylline
Brand name: Phyllocontin, Truphylline
Synonyms: Aminophylline (injection), Aminophylline
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Acyclovir (Systemic)-AminoProtect
- Acyclovir (Systemic)-Aminosalicylate sodium
- Acyclovir (Systemic)-Aminosalicylic Acid
- Acyclovir (Systemic)-Aminosyn
- Acyclovir (Systemic)-Aminosyn 10%
- Acyclovir (Systemic)-Aminosyn II
- Aminophylline Tablets-Acyclovir and Hydrocortisone
- Aminophylline Tablets-Acyclovir and hydrocortisone topical
- Aminophylline Tablets-Acyclovir and hydrocortisone Topical application
- Aminophylline Tablets-Acyclovir Buccal mucosa
- Aminophylline Tablets-Acyclovir Buccal Tablets
- Aminophylline Tablets-Acyclovir Capsules