Acys-5 and Ifosfamide and Mesna Injection
Determining the interaction of Acys-5 and Ifosfamide and Mesna Injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:When n-acetylcysteine is administered with ifosfamide, it does not interfere with the antineoplastic effects of ifosfamide. However, n-acetylcysteine does appear to interact with some metabolites of ifosfamide and to reduce toxicity to the kidney, ureters, bladder, and urethra.
- Holdiness MR "Clinical pharmacokinetics of N-acetylcysteine." Clin Pharmacokinet 20 (1991): 123-34
- Morgan LR, Holdiness MR, Gillen LE "N-acetylcysteine: its bioavailability and interaction with ifosfamide metabolites." Semin Oncol 10 (1 Suppl) (1983): 56-61
Generic Name: acetylcysteine
Brand name: Mucomyst-10, Cetylev
Synonyms: Acys-5 (Oral)
Generic Name: ifosfamide / mesna
Brand name:
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Acys-5-Ifosfamide Intravenous
- Acys-5-Ilaris
- Acys-5-Ilevro
- Acys-5-Iloperidone
- Acys-5-Iloprost
- Acys-5-Iloprost inhalation
- Ifosfamide and Mesna Injection-Aczone
- Ifosfamide and Mesna Injection-Aczone Topical
- Ifosfamide and Mesna Injection-Adacel
- Ifosfamide and Mesna Injection-Adacel Intramuscular
- Ifosfamide and Mesna Injection-Adacel TDAP
- Ifosfamide and Mesna Injection-Adagen