Adalat CC and Pulmicort Turbuhaler
Determining the interaction of Adalat CC and Pulmicort Turbuhaler and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Budesonide may reduce the effects of NIFEdipine in lowering blood pressure. The interaction is most likely to occur when budesonide is used for more than a week, since prolonged use can cause sodium and water retention. Let your doctor know if you experience sudden, unexplained weight gain or swelling of the hands, ankles, or feet. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Corticosteroids may antagonize the effects of antihypertensive medications by inducing sodium and fluid retention. These effects may be more common with the natural corticosteroids (cortisone, hydrocortisone) because they have greater mineralocorticoid activity. Conversely, some calcium channel blockers such as diltiazem and verapamil may increase corticosteroid plasma levels and effects by inhibiting their clearance via CYP450 3A4 metabolism.
MANAGEMENT: Patients on prolonged (i.e., longer than about a week) or high-dose corticosteroid therapy should have blood pressure, electrolyte levels, and body weight monitored regularly, and be observed for the development of edema and congestive heart failure. The dosages of antihypertensive medications may require adjustment.
- "Multum Information Services, Inc. Expert Review Panel"
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: nifedipine
Brand name: Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL, Adalat
Synonyms: n.a.
Generic Name: budesonide
Brand name: Pulmicort Flexhaler, Pulmicort Respules, Entocort EC, Uceris
Synonyms: Pulmicort Turbuhaler (Inhalation), Pulmicort
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Adalat CC-PulmoSal
- Adalat CC-Pulmozyme
- Adalat CC-Puralor Ci
- Adalat CC-PureFe Plus
- Adalat CC-Purelax
- Adalat CC-PureVit DualFe Plus
- Pulmicort Turbuhaler-Adalimumab
- Pulmicort Turbuhaler-Adalimumab Prefilled Pens and Syringes
- Pulmicort Turbuhaler-Adalimumab Subcutaneous
- Pulmicort Turbuhaler-Adalimumab Vials
- Pulmicort Turbuhaler-Adalimumab-adbm Subcutaneous
- Pulmicort Turbuhaler-Adalimumab-atto Subcutaneous