Adalat CC and Repaglinide and Metformin Tablets
Determining the interaction of Adalat CC and Repaglinide and Metformin Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using NIFEdipine together with metFORMIN may increase the effects of metFORMIN, which may lead to a life-threatening condition called lactic acidosis This can cause weakness, increasing sleepiness, slow heart rate, muscle pain, shortness of breath, stomach pain, feeling light-headed, and fainting. Talk with your doctor before using NIFEdipine while you are using metFORMIN. You may need a dose adjustment and you may need to check your blood sugar more often. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Nifedipine may increase plasma concentrations of metformin by increasing the extent of absorption. Increased metformin levels may increase the risk of lactic acidosis.
MANAGEMENT: If nifedipine and metformin must be used together, cautious titration of metformin dosage is recommended. Increased metformin levels may increase the risk of lactic acidosis. Patients should be advised to monitor their blood glucose and to promptly notify their physician if they experience possible signs of lactic acidosis such as malaise, myalgia, respiratory distress, hyperventilation, slow or irregular heartbeat, somnolence, abdominal upset, or other unusual symptoms.
- "Product Information. Glucophage (metformin)." Bristol-Myers Squibb, Princeton, NJ.
Generic Name: nifedipine
Brand name: Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL, Adalat
Synonyms: n.a.
Generic Name: metformin / repaglinide
Brand name: PrandiMet
Synonyms: Metformin and repaglinide, Repaglinide and Metformin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Adalat CC-Repaglinide Tablets
- Adalat CC-Repan
- Adalat CC-Repara Silver Nitrate Applicators
- Adalat CC-Replace
- Adalat CC-Replace Without Iron
- Adalat CC-Replesta
- Repaglinide and Metformin Tablets-Adalimumab
- Repaglinide and Metformin Tablets-Adalimumab Prefilled Pens and Syringes
- Repaglinide and Metformin Tablets-Adalimumab Subcutaneous
- Repaglinide and Metformin Tablets-Adalimumab Vials
- Repaglinide and Metformin Tablets-Adalimumab-adbm Subcutaneous
- Repaglinide and Metformin Tablets-Adalimumab-atto Subcutaneous