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Adalimumab-adbm Subcutaneous and Tuberculin Tests

Determining the interaction of Adalimumab-adbm Subcutaneous and Tuberculin Tests and the possibility of their joint administration.

Check result:

Adalimumab-adbm Subcutaneous <> Tuberculin Tests

Relevance: 19.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

If you are currently being treated or have recently been treated with adalimumab, you should let your doctor know before receiving tuberculin purified protein derivative. Depending on the dose and length of time you have been on adalimumab, you may have a reduced response to the skin test. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Immunosuppressed patients may have diminished response to diagnostic skin test antigens due to suppression of cell-mediated, delayed-type hypersensitivity. Falsely insignificant or false-negative results may occur in such patients, which may include those who have recently received or are receiving immunosuppressive agents, antilymphocyte globulins, alkylating agents, antimetabolites, radiation, some antirheumatic agents, high dosages of corticosteroids or adrenocorticotropic agents (e.g., greater than 10 mg/day or 1 mg/kg/day of prednisone or equivalent for more than 2 weeks), or long-term topical or inhaled corticosteroids.

MANAGEMENT: Clinicians should be aware of the potential for falsely insignificant or false-negative results when administering diagnostic skin test antigens to patients treated with immunosuppressive agents.

References

"Product Information. Candin (candida albicans extract)." Nielsen Biosciences Inc, San Diego, CA.
"Product Information. MSTA Mumps Skin Test Antigen (mumps skin test antigen)." Aventis Pharmaceuticals, Swiftwater, PA.
"Product Information. Spherulin (coccidioidin skin test)." ALK Laboratories Inc, Wallingford, CT.
"Product Information. Multitest CMI (skin test antigens, multiple)." Aventis Pharmaceuticals, Swiftwater, PA.
"Product Information. Histolyn-Cyl (histoplasmin)." ALK Laboratories Inc, Wallingford, CT.
"Product Information. Tuberculin PPD (Mantoux) (tuberculin purified protein derivative)." Connaught Laboratories Ltd, Toronto, ON.

Adalimumab-adbm Subcutaneous

Generic Name: adalimumab

Brand name: Humira, Humira Pen, Humira Pen Crohns/UlcerColit/HidraSuppur, Humira Pen Psoriasis/Uveitis Starter Package, Humira Pediatric, Humira Pediatric Crohn's Disease Starter Pack, Humira Pre-Filled Syringe, Humira Pen Psoriasis/Uveitis/Adol HidraSuppur Starter Pack, Humira Pen Crohns/Ulcer Colitis/Hidradenitis Suppurati StrPk

Synonyms: Adalimumab

What is Adalimumab-adbm Subcutaneous?

Tuberculin Tests

Generic Name: tuberculin purified protein derivative

Brand name: Aplisol, Tubersol

Synonyms: n.a.

What is Tuberculin Tests?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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