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Adderall XR and Delavirdine Mesylate

Determining the interaction of Adderall XR and Delavirdine Mesylate and the possibility of their joint administration.

Check result:
Adderall XR <> Delavirdine Mesylate
Relevance: 05.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using amphetamine together with delavirdine may increase the effects of amphetamine. Contact your doctor if you experience restlessness, tremor, rapid breathing, confusion, hallucinations, panic, aggressiveness, nausea, vomiting, diarrhea, an irregular heartbeat, and seizures. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor

Professional:

MONITOR: According to the product labeling for delavirdine, coadministration of the drug may increase the plasma concentrations of amphetamines. The proposed mechanism is delavirdine inhibition of the CYP450 2D6 metabolism of amphetamines.

MANAGEMENT: Caution is advised if amphetamines are prescribed in combination with delavirdine. Patients should be monitored for excessive anorectic and central nervous system stimulant effects of amphetamines.

References
  • "Product Information. Rescriptor (delavirdine)." Pharmacia and Upjohn, Kalamazoo, MI.
Adderall XR

Generic Name: amphetamine / dextroamphetamine

Brand name: Adderall, Adderall XR, Mydayis

Synonyms: n.a.

Delavirdine Mesylate

Generic Name: delavirdine

Brand name: Rescriptor

Synonyms: Delavirdine

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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