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Addyi and Phenohytro Elixir

Determining the interaction of Addyi and Phenohytro Elixir and the possibility of their joint administration.

Check result:

Addyi <> Phenohytro Elixir

Relevance: 24.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

PHENobarbital may significantly reduce the blood levels of flibanserin, which may make the medication ineffective or less effective in treating your condition. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Coadministration with potent inducers of CYP450 3A4 may significantly decrease the plasma concentrations of flibanserin, which is primarily metabolized by CYP450 3A4 and, to a lesser extent, by CYP450 2C19. In 24 healthy female subjects, administration of a single 100 mg dose of flibanserin following pretreatment with the potent CYP450 3A4 inducer rifampin (600 mg once daily for 7 days) resulted in a 95% decrease in flibanserin exposure. Loss of therapeutic efficacy may occur.

MANAGEMENT: Concomitant use of flibanserin with potent CYP450 3A4 inducers should generally be avoided.

References

"Product Information. Addyi (flibanserin)." Sprout Pharmaceuticals, Raleigh, NC.

Addyi

Generic Name: flibanserin

Brand name: Addyi

Synonyms: n.a.

What is Addyi?

Phenohytro Elixir

Generic Name: atropine / hyoscyamine / phenobarbital / scopolamine

Brand name: Donnatal, D-Tal, Phenohytro, Chardonna-2, Hyosophen, Donnapine, Elixiral, Bellatal, Spasmolin, Haponal, Antispas, Barbidonna, Donnatal Extentabs, Antispasmodic, Bellalphen, Donnaphen, Spasquid, Alkabel-SR, Bellatal ER, Servira, PB-Hyos, Quadrapax, Phenobarbital with Belladonna Alkaloids

Synonyms: Phenohytro

What is Phenohytro Elixir?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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