Adempas Tablets and DAUNOrubicin and Cytarabine

• Generic Name: riociguat
• Dosage Forms: tablet, film coated
• Other Brand Names: Adempas

Riociguat is used to treat chronic thromboembolic pulmonary hypertension (CTEPH) in people who cannot be treated with surgery, or in people who have undergone surgery but still have symptoms. Riociguat can treat certain symptoms of CTEPH and can improve your ability to exercise.

Riociguat is also used to treat pulmonary arterial hypertension (PAH). Riociguat can improve your ability to exercise and help prevent PAH from getting worse.

Riociguat is available to women only under a special program. You must be registered in the program and understand the risks and benefits of riociguat.

Riociguat may also be used for purposes not listed in this medication guide.

• Generic Name: cytarabine liposomal / daunorubicin liposomal
• Dosage Forms: n.a.
• Other Brand Names: Vyxeos

Treatment of newly diagnosed therapy-related AML (t-AML; secondary AML) or AML with myelodysplasia-related changes (AML-MRC) in adults (designated an orphan drug by FDA for this use).

May be used for remission induction as well as consolidation therapy.

Evidence supporting efficacy is based principally on a study performed in patients with high-risk AML (i.e., patients >60 years of age with t-AML or AML-MRC).