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Adenoscan and Carbamazepine Extended-Release Capsules (Carbatrol)

Determining the interaction of Adenoscan and Carbamazepine Extended-Release Capsules (Carbatrol) and the possibility of their joint administration.

Check result:
Adenoscan <> Carbamazepine Extended-Release Capsules (Carbatrol)
Relevance: 23.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using adenosine together with carBAMazepine may alter the effects of adenosine. This can cause increased side effects or cause your condition to change. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Carbamazepine has been reported to increase the degree of heart block produced by other agents, including adenosine. In vitro data show that carbamazepine inhibits adenosine receptor binding.

MANAGEMENT: Electrocardiographic rhythm monitoring and monitoring for increased cardiovascular toxicity are recommended during coadministration.

References
  • Fujiwara Y, Sato M, Otsuki S "Interaction of carbamazepine and other drugs with adenosine (A1 and A2) receptors." Psychopharmacology (Berl) 90 (1986): 332-5
  • "Product Information. Adenocard (adenosine)." Fujisawa, Deerfield, IL.
Adenoscan

Generic Name: adenosine

Brand name: Adenocard, Adenoscan, Adeno-jec, My-O-Den, Myoden

Synonyms: n.a.

Carbamazepine Extended-Release Capsules (Carbatrol)

Generic Name: carbamazepine

Brand name: Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Tegretol, Tegretol XR

Synonyms: Carbamazepine, CarBAMazepine

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.