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Adipex-P and Guaifenesin and Phenylephrine Drops

Determining the interaction of Adipex-P and Guaifenesin and Phenylephrine Drops and the possibility of their joint administration.

Check result:
Adipex-P <> Guaifenesin and Phenylephrine Drops
Relevance: 06.12.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Both phenylephrine and phentermine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Central nervous system (CNS) stimulants, particularly the amphetamines, can potentiate the adrenergic response to vasopressors and other sympathomimetic agents. Additive increases in blood pressure and heart rate may occur due to enhanced peripheral sympathetic activity.

MANAGEMENT: Caution is advised if CNS stimulants are used with vasopressors or other sympathomimetic agents. Pulse and blood pressure should be closely monitored.

References
  • "Product Information. Sanorex (mazindol)" Novartis Pharmaceuticals, East Hanover, NJ.
  • "Product Information. Strattera (atomoxetine)." Lilly, Eli and Company, Indianapolis, IN.
  • Rosenblatt JE, Lake CR, van Kammen DP, Ziegler MG, Bunney WE Jr "Interactions of amphetamine, pimozide, and lithium on plasma norepineophrine and dopamine-beta-hydroxylase in schizophrenic patients." Psychiatry Res 1 (1979): 45-52
  • "Product Information. Tenuate (diethylpropion)" Aventis Pharmaceuticals, Swiftwater, PA.
  • "Product Information. Adderall (amphetamine-dextroamphetamine)" Shire Richwood Pharmaceutical Company, Florence, KY.
  • "Product Information. Focalin (dexmethylphenidate)." Mikart Inc, Atlanta, GA.
  • Cavanaugh JH, Griffith JD, Oates JA "Effect of amphetamine on the pressor response to tyramine: formation of p-hydroxynorephedrine from amphetamine in man." Clin Pharmacol Ther 11 (1970): 656
Adipex-P

Generic Name: phentermine

Brand name: Adipex-P, Lomaira, Suprenza

Synonyms: n.a.

Guaifenesin and Phenylephrine Drops

Generic Name: guaifenesin / phenylephrine

Brand name: Aldex G, Aquatab D, Deconex, Deconex IR, Donatussin Drops, D-Phen 1000, Duravent PE, Gilphex TR, Liquibid-PD, MucaphEd, Nariz, Prolex D, Sudafed PE Non-Drying Sinus, Supress-PE, Triaminic Chest & Nasal Congestion, Xpect-PE, Sinupan, Deconsal Pediatric, Efasin, Amidal, Chemdal, Quindal, Endal, Liquibid-D, Rescon-GG, SINUvent PE, Entex LA, Entex, Crantex, Crantex LA Capsules, Amitex LA, Entex ER, Duraphen II, Crantex ER, Liquibid-D 1200, Phenavent LA, Phenavent D, Sina-12X, Deconsal II, Guaifed Caps, Guaifed PD, Phenavent, Tussbid, Phenavent PED, Nescon-PD, Pendex, Prolex PD, Aldex, Nasex, Crantex LA Tablets, Duratuss, Duratuss GP, Lusonex, Sitrex, Guaiphen-PD, Wellbid-D, Wellbid-D 1200, Despec, Xedec, Nasex-G, Gentex LA, Guaiphen-D 600, Guaiphen-D 1200, Simuc, Zotex GPX, Duomax, Guaifen PE, Norel EX, Nexphen PD, Respa-PE, Reluri, Duraphen 1000, Dynex LA, Sudex, Extendryl G, Maxiphen, Ambi 40/1000, MontePhen, Xedec II, Simuc-GP, Duratuss PE, Sitrex PD, Refenesen PE, Mydex, Medent-PE, Genexa LA, Nazarin, J-Max, Mucus Relief Sinus, Robitussin Head & Chest Congestion, Visonex, Zyrphen, PE-Guai, Guiadex PD, D-Tab, ExeTuss, ExeTuss-GP, Mucinex Children's Cold, Quintex, Guiatex PE, Fenesin PE IR, Medent-PEI, Liquibid PD-R, Liquibid D-R, Zoden Drops, Entex LQ, Tussi-Pres PE, Lusair, Reese Onetab Congestion & Cough, ED Bron GP, Relcof IR, Giltuss Sinus & Congestion, Zotex-GP

Synonyms: Guaifenesin and phenylephrine, Guaifenesin and Phenylephrine

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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