Ado-trastuzumab emtansine and Omalizumab Subcutaneous

• Generic Name: ado-trastuzumab emtansine
• Dosage Forms: n.a.
• Other Brand Names: Kadcyla

Ado-trastuzumab emtansine is used to treat a HER2-positive breast cancer. ado-trastuzumab emtansine is used both for early breast cancer and for breast cancer that has spread to other parts of the body (metastatic).

Ado-trastuzumab emtansine is usually given after other treatments have failed.

Kadcyla (ado-trastuzumab) should not be used in place of Herceptin (trastuzumab).

Ado-trastuzumab emtansine may also be used for purposes not listed in this medication guide.

• Generic Name: omalizumab
• Dosage Forms: n.a.
• Other Brand Names: Xolair, Xolair Prefilled Syringe

Omalizumab injection is used to treat moderate to severe persistent allergic asthma. It is used when a patient's asthma has not been controlled sufficiently on other asthma medicines. Omalizumab will not relieve an asthma attack that has already started.

Omalizumab injection is also used to treat chronic idiopathic urticaria (CIU) in patients who continue to have hives that are not controlled by an antihistamine (allergy medicine).

Omalizumab is a medicine called an IgE blocker. IgE is short for immunoglobulin E, a substance that occurs naturally in the body in small amounts. This substance plays an important role in allergic asthma. When people with allergic asthma breathe in a year-round allergen, such as cat or dog dander, their bodies make more IgE. This may cause a series of reactions in your body that can lead to asthma attacks and symptoms. Omalizumab works by helping to block IgE.

Omalizumab is to be given only by or under the direct supervision of your doctor.