Adrenalin Injection and Canakinumab

• Generic Name: epinephrine
• Dosage Forms: injection
• Other Brand Names: Adrenalin, Auvi-Q, Epinephrinesnap-EMS, EpiPen 2-Pak, EpiPen JR 2-Pak, EPIsnap, Symjepi, Auvi-Q Auto-injector, Primatene Mist Inhaler, Adrenaclick, EpiPen, Twinject, Primatene Mist

Epinephrine injection is used for emergency treatment of severe allergic reactions (including anaphylaxis) to insect bites or stings, medicines, foods, or other substances. It is also used to treat anaphylaxis caused by unknown substances or triggered by exercise.

This medicine is available only with your doctor's prescription.

• Generic Name: canakinumab
• Dosage Forms: n.a.
• Other Brand Names: Ilaris

Canakinumab is a monoclonal antibody that blocks certain proteins in the body that can affect inflammation and other immune responses. Canakinumab is used to treat certain types of periodic fever syndromes, sometimes called auto-inflammatory syndromes.

Periodic fever syndromes are rare and often inherited conditions caused by mutations in certain genes; usually genes that are involved in producing a certain protein or enzyme in the body. People with a periodic fever syndrome have episodes of fever and inflammation without other causes such as infection or virus.

Canakinumab is used to treat the following periodic fever syndromes in adults and children who are at least 4 years old:

• Cryopyrin-Associated Periodic Syndromes (CAPS), including Familial Cold Autoinflammatory Syndrome and Muckle-Wells Syndrome.
• Tumor Necrosis Factor Receptor Associated Periodic Syndrome (TRAPS).
• Hyperimmunoglobulin D Syndrome (HIDS), also called Mevalonate Kinase Deficiency (MKD).
• Familial Mediterranean Fever (FMF).

Canakinumab is also used to treat Sudden Juvenile Idiopathic Arthritis (SJIA) in children who are at least 2 years old.

Canakinumab may also be used for purposes not listed in this medication guide.