Drug search by name

Adrucil and Cetuximab Intravenous

Determining the interaction of Adrucil and Cetuximab Intravenous and the possibility of their joint administration.

Check result:

Adrucil <> Cetuximab Intravenous

Relevance: 04.04.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using fluorouracil together with cetuximab may increase the risk of serious side effects such as heart attack, heart failure, and a condition known as "hand-foot syndrome" that is caused by blood leakage from small vessels of the hands and feet. Contact your doctor if you experience chest pain, chest tightness, difficulty breathing, and/or redness, tenderness, or peeling of the palms and soles. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: The concomitant use of parenteral fluorouracil or capecitabine with cetuximab may increase the frequency of myocardial ischemia (infarction and congestive heart failure) and palmar-plantar erythrodysesthesia (hand-foot syndrome).

MANAGEMENT: Patients who are receiving combination treatment with cetuximab and other antineoplastic drugs should be monitored for adverse effects.

References

EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports. Available from: URL: http://www.ema.europa.eu/ema/index.jsp?curl=pages/includes/medicines/medicines_landingpage.jsp&mid."
Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Cerner Multum, Inc. "Australian Product Information." O 0

Adrucil

Generic Name: fluorouracil

Brand name: Adrucil

Synonyms: Adrucil (injection)

What is Adrucil?

Cetuximab Intravenous

Generic Name: cetuximab

Brand name: Erbitux

Synonyms: Cetuximab

What is Cetuximab Intravenous?

+ Add a drug Remove all

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

The list of popular interactions