Afrezza and DAUNOrubicin and Cytarabine

• Generic Name: insulin inhalation, rapid acting
• Dosage Forms: inhalation powder, metered
• Other Brand Names: Afrezza, Exubera, Exubera, EXUBERA Combination Pack 12, EXUBERA Combination Pack 15, EXUBERA Kit, Afrezza 4 unit- 8 unit, Afrezza 8 unit- 12 unit, Afrezza Titration Pack

Afrezza (insulin inhalation) is a rapid-acting form of human insulin that is inhaled through the mouth. Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Afrezza inhalation is a fast-acting insulin that starts to work about 15 minutes after inhalation, peaks in about 1 hour, and keeps working for 2 to 4 hours.

Afrezza inhalation is used to improve blood sugar control in adults with diabetes mellitus.

If you have type 1 diabetes, you will also need to use a long-acting injectable insulin.

If you have type 2 diabetes, Afrezza may be the only medicine you need to control your blood sugar. However, your doctor may prescribe a long-acting injectable insulin or a diabetes medicine you take by mouth.

• Generic Name: cytarabine liposomal / daunorubicin liposomal
• Dosage Forms: n.a.
• Other Brand Names: Vyxeos

Treatment of newly diagnosed therapy-related AML (t-AML; secondary AML) or AML with myelodysplasia-related changes (AML-MRC) in adults (designated an orphan drug by FDA for this use).

May be used for remission induction as well as consolidation therapy.

Evidence supporting efficacy is based principally on a study performed in patients with high-risk AML (i.e., patients >60 years of age with t-AML or AML-MRC).