Afrezza and Orfadin

• Generic Name: insulin inhalation, rapid acting
• Dosage Forms: inhalation powder, metered
• Other Brand Names: Afrezza, Exubera, Exubera, EXUBERA Combination Pack 12, EXUBERA Combination Pack 15, EXUBERA Kit, Afrezza 4 unit- 8 unit, Afrezza 8 unit- 12 unit, Afrezza Titration Pack

Afrezza (insulin inhalation) is a rapid-acting form of human insulin that is inhaled through the mouth. Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Afrezza inhalation is a fast-acting insulin that starts to work about 15 minutes after inhalation, peaks in about 1 hour, and keeps working for 2 to 4 hours.

Afrezza inhalation is used to improve blood sugar control in adults with diabetes mellitus.

If you have type 1 diabetes, you will also need to use a long-acting injectable insulin.

If you have type 2 diabetes, Afrezza may be the only medicine you need to control your blood sugar. However, your doctor may prescribe a long-acting injectable insulin or a diabetes medicine you take by mouth.

• Generic Name: nitisinone
• Dosage Forms: capsule
• Other Brand Names: Orfadin, Nityr

Orfadin works by preventing the body from breaking down an amino acid called tyrosine and by keeping other toxic substances from building up and causing harm to your liver or kidneys.

Orfadin is used to treat a rare genetic condition called hereditary tyrosinemia type 1 (HT-1). HT-1 is a metabolic disorder that occurs when the body does not produce enough of an enzyme that breaks down proteins from certain foods. This condition occurs most often in young babies.

Orfadin may also be used for purposes not listed in this medication guide.