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Agalsidase beta and Pacerone

Determining the interaction of Agalsidase beta and Pacerone and the possibility of their joint administration.

Check result:

Agalsidase beta <> Pacerone

Relevance: 02.07.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using amiodarone and agalsidase beta is not recommended. Using these drugs together can alter the levels of agalsidase beta. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

CONTRAINDICATED: Amiodarone, chloroquine, and gentamicin may have the potential to inhibit intracellular alpha-galactosidase activity, thereby reducing the pharmacologic effects of agalsidase alfa and agalsidase beta. Clinical data have not been reported.

MANAGEMENT: Agalsidase should not be coadministered with amiodarone, chloroquine, or gentamicin.

References

"Product Information. Replagal (agalsidase alfa)." Transkaryotic Therapies Inc, Cambridge, MA.

Agalsidase beta

Generic Name: agalsidase beta

Brand name: Fabrazyme

Synonyms: Agalsidase Beta

What is Agalsidase beta?

Pacerone

Generic Name: amiodarone

Brand name: Pacerone, Cordarone, Nexterone

Synonyms: n.a.

What is Pacerone?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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