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Agalsidase beta Intravenous and Aralen Phosphate

Determining the interaction of Agalsidase beta Intravenous and Aralen Phosphate and the possibility of their joint administration.

Check result:

Agalsidase beta Intravenous <> Aralen Phosphate

Relevance: 22.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using chloroquine and agalsidase beta is not recommended. Using these drugs together can alter the levels of agalsidase beta. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

CONTRAINDICATED: Amiodarone, chloroquine, and gentamicin may have the potential to inhibit intracellular alpha-galactosidase activity, thereby reducing the pharmacologic effects of agalsidase alfa and agalsidase beta. Clinical data have not been reported.

MANAGEMENT: Agalsidase should not be coadministered with amiodarone, chloroquine, or gentamicin.

References

"Product Information. Replagal (agalsidase alfa)." Transkaryotic Therapies Inc, Cambridge, MA.

Agalsidase beta Intravenous

Generic Name: agalsidase beta

Brand name: Fabrazyme

Synonyms: Agalsidase beta, Agalsidase Beta

What is Agalsidase beta Intravenous?

Aralen Phosphate

Generic Name: chloroquine

Brand name: Aralen Phosphate, Aralen Hydrochloride

Synonyms: n.a.

What is Aralen Phosphate?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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